Examination of pectoral water DNA can offer malignant tumor thorax to accumulate

The basis published on May 15 " international cancer magazine " (Int J Cancer 2007;120:2191-2195. ) the discovery that a Japan that go up studies, know exactly about sth is planted tumor restrains gene to exceed methylic the pectoral water DNA that change and thorax of malignant tumor sex accumulate fluid relevant.

Dr. Hideki Katayama of national hospital of NHO Sanyo of   Japan and its work in the same placing checked thorax of sex of 47 malignant tumor to accumulate fluid and 34 blame the pectoral water that malignant tumor thorax accumulates fluid patient, search 5 kinds of tumour to restrain gene DNA to exceed methylic the evidence that turn.

  investigator reports, with without super- methylic the patient posture that change is compared, 5 kinds restrain 4 kinds in gene (MGMT, p16-INK4a, RASSFIA, exceed with RAR-beta) methylic the likelihood that the patient that turn produces malignant tumor thorax to accumulate fluid increases 5.68 times. Gene of the 5th kind of cancer, of DAPK super- methylic change accumulate fluid with malignant tumor thorax not relevant, but the time length with smoking is relevant. One or more gene is methylic the sensitivity that changes pair of malignant tumor thorax to accumulate fluid to diagnose, particularity and positive forecast action to be respectively 59.6% , 79.4% with 80.0% .

  their summary says, tumour of pectoral water DNA restrains gene to open mover methylic changing a likelihood is a kind of when malignant tumor thorax accumulates fluid worthy diagnostic mark thing.